50% Women's
breasts are dense. High breast density on a mammogram is known to obscure
cancer, often described as seeking a polar bear in a snowstorm that can lead to
false negative results–results where early cancer is not identified and breast
cancer is therefore detected at a later stage. It is diagnosed with the later
breast cancer, the lower chance of survival.
Despite this, in their recommendations
for using additional testing on women with dense breasts, clinical guidelines
vary from state to state. In fact, for women with dense breasts, many states do
not offer any additional resources.
BI-RADS 3
vs. BI-RADS 4A or the "Gray Zone": A challenge facing health care
providers is whether women with unclear findings need a biopsy to detect breastcancer. Approximately 1.7 million breast biopsies are performed annually with
70 to 90 percent resulting in a false positive result due to benign breast
tissue that can mimic the appearance of breast cancer, creating a stressful
situation for patients that otherwise could be avoided.
To enhance
the accuracy of early detection of breast cancer, complementary blood-based
approaches are being developed to help address current image limitations. By
using new methods to complement current methods of detection, health care
providers will be able to improve the accuracy and timeliness of detection of
breast cancer and help reduce the consequences of false positive and negative
outcomes. Earlier detection is directly correlated with increased survival,
with early stage breast cancer diagnosis resulting in a 5-year survival rate of
99 percent.
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